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Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells

BACKGROUND: Mucin alterations are a common feature of esophageal neoplasia, and alterations in MUC2 mucin have been associated with tumor progression in the esophagus. Bile acids have been linked to esophageal adenocarcinoma and mucin secretion, but their effects on mucin gene expression in human es...

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Detalles Bibliográficos
Autores principales: Wu, JianTao, Gong, Jun, Geng, Juan, Song, YinXue
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596174/
https://www.ncbi.nlm.nih.gov/pubmed/19014523
http://dx.doi.org/10.1186/1471-2407-8-333