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The Population Genetics of dN/dS

Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which represent substitutions that have fixed along indep...

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Detalles Bibliográficos
Autores principales: Kryazhimskiy, Sergey, Plotkin, Joshua B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596312/
https://www.ncbi.nlm.nih.gov/pubmed/19081788
http://dx.doi.org/10.1371/journal.pgen.1000304