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The Population Genetics of dN/dS
Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which represent substitutions that have fixed along indep...
Autores principales: | Kryazhimskiy, Sergey, Plotkin, Joshua B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596312/ https://www.ncbi.nlm.nih.gov/pubmed/19081788 http://dx.doi.org/10.1371/journal.pgen.1000304 |
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