Deciphering the Ligand-binding Sites in the Borrelia burgdorferi Complement Regulator-acquiring Surface Protein 2 Required for Interactions with the Human Immune Regulators Factor H and Factor H-like Protein 1

Borrelia burgdorferi, the etiologic agent of Lyme disease, employs sophisticated means to evade killing by its mammalian hosts. One important immune escape mechanism is the inhibition of complement activation mediated by interactions of the host-derived immune regulators factor H (CFH) and factor H-...

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Detalles Bibliográficos
Autores principales: Siegel, Corinna, Schreiber, Johanna, Haupt, Katrin, Skerka, Christine, Brade, Volker, Simon, Markus M., Stevenson, Brian, Wallich, Reinhard, Zipfel, Peter F., Kraiczy, Peter
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596382/
https://www.ncbi.nlm.nih.gov/pubmed/18824548
http://dx.doi.org/10.1074/jbc.M805844200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596382/
https://www.ncbi.nlm.nih.gov/pubmed/18824548
http://dx.doi.org/10.1074/jbc.M805844200

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