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Structure of an isolated unglycosylated antibody C(H)2 domain

The C(H)2 (C(H)3 for IgM and IgE) domain of an antibody plays an important role in mediating effector functions and preserving antibody stability. It is the only domain in human immunoglobulins (Igs) which is involved in weak interchain protein–protein interactions with another C(H)2 domain solely t...

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Detalles Bibliográficos
Autores principales: Prabakaran, Ponraj, Vu, Bang K., Gan, Jianhua, Feng, Yang, Dimitrov, Dimiter S., Ji, Xinhua
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596763/
https://www.ncbi.nlm.nih.gov/pubmed/18931413
http://dx.doi.org/10.1107/S0907444908025274