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Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif

Parasites of the Leishmania genus can rapidly alter several macrophage (MØ) signalling pathways in order to tame down the innate immune response and inflammation, therefore favouring their survival and propagation within their mammalian host. Having recently reported that Leishmania and bacterial LP...

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Detalles Bibliográficos
Autores principales: Abu-Dayyeh, Issa, Shio, Marina Tiemi, Sato, Shintaro, Akira, Shizuo, Cousineau, Benoit, Olivier, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596967/
https://www.ncbi.nlm.nih.gov/pubmed/19104650
http://dx.doi.org/10.1371/journal.pntd.0000305