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BAX Activation is Initiated at a Novel Interaction Site

BAX is a pro-apoptotic protein of the BCL-2 family stationed in the cytosol until activated by a diversity of stress stimuli to induce cell death. Anti-apoptotic proteins such as BCL-2 counteract BAX-mediated cell death. Although an interaction site that confers survival functionality has been defin...

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Detalles Bibliográficos
Autores principales: Gavathiotis, Evripidis, Suzuki, Motoshi, Davis, Marguerite L., Pitter, Kenneth, Bird, Gregory H., Katz, Samuel G., Tu, Ho-Chou, Kim, Hyungjin, Cheng, Emily H.-Y., Tjandra, Nico, Walensky, Loren D.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597110/
https://www.ncbi.nlm.nih.gov/pubmed/18948948
http://dx.doi.org/10.1038/nature07396