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Essential Role of TGF-β/Smad Pathway on Statin Dependent Vascular Smooth Muscle Cell Regulation

BACKGROUND: The 3-hydroxy-3-methylglutaryl CoA reductase inhibitors (also called statins) exert proven beneficial effects on cardiovascular diseases. Recent data suggest a protective role for Transforming Growth Factor-β (TGF-β) in atherosclerosis by regulating the balance between inflammation and e...

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Detalles Bibliográficos
Autores principales: Rodríguez-Vita, Juan, Sánchez-Galán, Eva, Santamaría, Beatriz, Sánchez-López, Elsa, Rodrigues-Díez, Raquel, Blanco-Colio, Luís Miguel, Egido, Jesús, Ortiz, Alberto, Ruiz-Ortega, Marta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597201/
https://www.ncbi.nlm.nih.gov/pubmed/19088845
http://dx.doi.org/10.1371/journal.pone.0003959