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Development of Broad‐Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CL(pro)

Coronaviruses comprise a large group of RNA viruses with diverse host specificity. The emergence of highly pathogenic strains like the SARS coronavirus (SARS‐CoV), and the discovery of two new coronaviruses, NL‐63 and HKU1, corroborates the high rate of mutation and recombination that have enabled t...

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Detalles Bibliográficos
Autores principales: Bacha, Usman, Barrila, Jennifer, Gabelli, Sandra B., Kiso, Yoshiaki, Mario Amzel, L., Freire, Ernesto
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597651/
https://www.ncbi.nlm.nih.gov/pubmed/18611220
http://dx.doi.org/10.1111/j.1747-0285.2008.00679.x