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Surviving Mousepox Infection Requires the Complement System

Poxviruses subvert the host immune response by producing immunomodulatory proteins, including a complement regulatory protein. Ectromelia virus provides a mouse model for smallpox where the virus and the host's immune response have co-evolved. Using this model, our study investigated the role o...

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Detalles Bibliográficos
Autores principales: Moulton, Elizabeth A., Atkinson, John P., Buller, R. Mark L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597719/
https://www.ncbi.nlm.nih.gov/pubmed/19112490
http://dx.doi.org/10.1371/journal.ppat.1000249