Cargando…
Surviving Mousepox Infection Requires the Complement System
Poxviruses subvert the host immune response by producing immunomodulatory proteins, including a complement regulatory protein. Ectromelia virus provides a mouse model for smallpox where the virus and the host's immune response have co-evolved. Using this model, our study investigated the role o...
Autores principales: | Moulton, Elizabeth A., Atkinson, John P., Buller, R. Mark L |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597719/ https://www.ncbi.nlm.nih.gov/pubmed/19112490 http://dx.doi.org/10.1371/journal.ppat.1000249 |
Ejemplares similares
-
Comparative Pathogenesis, Genomics and Phylogeography of Mousepox
por: Mavian, Carla, et al.
Publicado: (2021) -
Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies
por: Parker, Scott, et al.
Publicado: (2009) -
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox – An animal model of smallpox
por: Parker, Scott, et al.
Publicado: (2012) -
Efficacy of therapeutic intervention with an oral ether–lipid analogue of cidofovir (CMX001) in a lethal mousepox model
por: Parker, Scott, et al.
Publicado: (2008) -
Caspase-Dependent Inhibition of Mousepox Replication by gzmB
por: Pardo, Julián, et al.
Publicado: (2009)