Ion Channel Clustering at the Axon Initial Segment and Node of Ranvier Evolved Sequentially in Early Chordates

In many mammalian neurons, dense clusters of ion channels at the axonal initial segment and nodes of Ranvier underlie action potential generation and rapid conduction. Axonal clustering of mammalian voltage-gated sodium and KCNQ (Kv7) potassium channels is based on linkage to the actin–spectrin cyto...

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Detalles Bibliográficos
Autores principales: Hill, Alexis S., Nishino, Atsuo, Nakajo, Koichi, Zhang, Giuxin, Fineman, Jaime R., Selzer, Michael E., Okamura, Yasushi, Cooper, Edward C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597720/
https://www.ncbi.nlm.nih.gov/pubmed/19112491
http://dx.doi.org/10.1371/journal.pgen.1000317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597720/
https://www.ncbi.nlm.nih.gov/pubmed/19112491
http://dx.doi.org/10.1371/journal.pgen.1000317

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