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Polymorphisms within the Novel Type 2 Diabetes Risk Locus MTNR1B Determine β-Cell Function

BACKGROUND: Very recently, a novel type 2 diabetes risk gene, i.e., MTNR1B, was identified and reported to affect fasting glycemia. Using our thoroughly phenotyped cohort of subjects at an increased risk for type 2 diabetes, we assessed the association of common genetic variation within the MTNR1B l...

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Detalles Bibliográficos
Autores principales: Staiger, Harald, Machicao, Fausto, Schäfer, Silke A., Kirchhoff, Kerstin, Kantartzis, Konstantinos, Guthoff, Martina, Silbernagel, Günther, Stefan, Norbert, Häring, Hans-Ulrich, Fritsche, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597741/
https://www.ncbi.nlm.nih.gov/pubmed/19088850
http://dx.doi.org/10.1371/journal.pone.0003962