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G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells

BACKGROUND: Atrazine, one of the most common pesticide contaminants, has been shown to up-regulate aromatase activity in certain estrogen-sensitive tumors without binding or activating the estrogen receptor (ER). Recent investigations have demonstrated that the orphan G-protein–coupled receptor 30 (...

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Detalles Bibliográficos
Autores principales: Albanito, Lidia, Lappano, Rosamaria, Madeo, Antonio, Chimento, Adele, Prossnitz, Eric R., Cappello, Anna Rita, Dolce, Vincenza, Abonante, Sergio, Pezzi, Vincenzo, Maggiolini, Marcello
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599758/
https://www.ncbi.nlm.nih.gov/pubmed/19079715
http://dx.doi.org/10.1289/ehp.11297