Loop B Is a Major Structural Component of the 5-HT(3) Receptor

The 5-HT(3) receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F). Here we have mutated 15 amino acid residues in and around loop B of the 5-HT(3) receptor (Ser-177 to Asn-191) to...

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Detalles Bibliográficos
Autores principales: Thompson, A. J., Lochner, M., Lummis, S. C. R.
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2008
Materias:
Channels, Receptors, and Electrical Signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599823/
https://www.ncbi.nlm.nih.gov/pubmed/18931259
http://dx.doi.org/10.1529/biophysj.108.135624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599823/
https://www.ncbi.nlm.nih.gov/pubmed/18931259
http://dx.doi.org/10.1529/biophysj.108.135624

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