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Loop B Is a Major Structural Component of the 5-HT(3) Receptor
The 5-HT(3) receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F). Here we have mutated 15 amino acid residues in and around loop B of the 5-HT(3) receptor (Ser-177 to Asn-191) to...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599823/ https://www.ncbi.nlm.nih.gov/pubmed/18931259 http://dx.doi.org/10.1529/biophysj.108.135624 |