Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

We suggest for the first time that the action of multivalent cations on microtubule dynamics can result from facilitated diffusion of GTP-tubulin to the microtubule ends. Facilitated diffusion can promote microtubule assembly, because, upon encountering a growing nucleus or the microtubule wall, ran...

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Detalles Bibliográficos
Autores principales: Mechulam, Alain, Chernov, Konstantin G., Mucher, Elodie, Hamon, Loic, Curmi, Patrick A., Pastré, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599886/
https://www.ncbi.nlm.nih.gov/pubmed/19119409
http://dx.doi.org/10.1371/journal.pcbi.1000255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599886/
https://www.ncbi.nlm.nih.gov/pubmed/19119409
http://dx.doi.org/10.1371/journal.pcbi.1000255

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