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Involvement of LPA(1 )receptor signaling in the reorganization of spinal input through Abeta-fibers in mice with partial sciatic nerve injury
Lysophosphatidic acid receptor subtype LPA(1 )is crucial for the initiation of neuropathic pain and underlying changes, such as up-regulation of Ca(2)+ channel α(2)δ-1 subunit in dorsal root ganglia (DRG), up-regulation of PKCγ in the spinal dorsal horn, and demyelination of dorsal root fibers. In t...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599895/ https://www.ncbi.nlm.nih.gov/pubmed/18854053 http://dx.doi.org/10.1186/1744-8069-4-46 |