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The Raf-1 inhibitor GW5074 and dexamethasone suppress sidestream smoke-induced airway hyperresponsiveness in mice

BACKGROUND: Sidestream smoke is closely associated with airway inflammation and hyperreactivity. The present study was designed to investigate if the Raf-1 inhibitor GW5074 and the anti-inflammatory drug dexamethasone suppress airway hyperreactivity in a mouse model of sidestream smoke exposure. MET...

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Detalles Bibliográficos
Autores principales: Lei, Ying, Cao, Yong-Xiao, Xu, Cang-Bao, Zhang, Yaping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599896/
https://www.ncbi.nlm.nih.gov/pubmed/18976506
http://dx.doi.org/10.1186/1465-9921-9-71