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Cytotoxicity Mechanism of Two Naphthoquinones (Menadione and Plumbagin) in Saccharomyces cerevisiae

BACKGROUND: Quinones are compounds extensively used in studies of oxidative stress due to their role in plants as chemicals for defense. These compounds are of great interest for pharmacologists and scientists, in general, because several cancer chemotherapeutic agents contain the quinone nucleus. H...

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Detalles Bibliográficos
Autores principales: Castro, Frederico Augusto Vieira, Mariani, Diana, Panek, Anita Dolly, Eleutherio, Elis Cristina Araújo, Pereira, Marcos Dias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600608/
https://www.ncbi.nlm.nih.gov/pubmed/19098979
http://dx.doi.org/10.1371/journal.pone.0003999