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Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

How focal adhesions (FAs) convert retrograde filamentous actin (F-actin) flow into traction stress on the extracellular matrix to drive cell migration is unknown. Using combined traction force and fluorescent speckle microscopy, we observed a robust biphasic relationship between F-actin speed and tr...

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Detalles Bibliográficos
Autores principales: Gardel, Margaret L., Sabass, Benedikt, Ji, Lin, Danuser, Gaudenz, Schwarz, Ulrich S., Waterman, Clare M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600750/
https://www.ncbi.nlm.nih.gov/pubmed/19075110
http://dx.doi.org/10.1083/jcb.200810060