SUMO-Specific Protease 2 Is Essential for Modulating p53-Mdm2 in Development of Trophoblast Stem Cell Niches and Lineages

SUMO-specific protease 2 (SENP2) modifies proteins by removing SUMO from its substrates. Although SUMO-specific proteases are known to reverse sumoylation in many defined systems, their importance in mammalian development and pathogenesis remains largely elusive. Here we report that SENP2 is highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiu, Shang-Yi, Asai, Naoya, Costantini, Frank, Hsu, Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602722/
https://www.ncbi.nlm.nih.gov/pubmed/19090619
http://dx.doi.org/10.1371/journal.pbio.0060310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602722/
https://www.ncbi.nlm.nih.gov/pubmed/19090619
http://dx.doi.org/10.1371/journal.pbio.0060310

Ejemplares similares