Exploring TAR–RNA aptamer loop–loop interaction by X-ray crystallography, UV spectroscopy and surface plasmon resonance

In HIV-1, trans-activation of transcription of the viral genome is regulated by an imperfect hairpin, the trans-activating responsive (TAR) RNA element, located at the 5′ untranslated end of all viral transcripts. TAR acts as a binding site for viral and cellular proteins. In an attempt to identify...

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Detalles Bibliográficos
Autores principales: Lebars, Isabelle, Legrand, Pierre, Aimé, Ahissan, Pinaud, Noël, Fribourg, Sébastien, Di Primo, Carmelo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602780/
https://www.ncbi.nlm.nih.gov/pubmed/18996893
http://dx.doi.org/10.1093/nar/gkn831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602780/
https://www.ncbi.nlm.nih.gov/pubmed/18996893
http://dx.doi.org/10.1093/nar/gkn831

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