A rugged free energy landscape separates multiple functional RNA folds throughout denaturation

The dynamic mechanisms by which RNAs acquire biologically functional structures are of increasing importance to the rapidly expanding fields of RNA therapeutics and biotechnology. Large energy barriers separating misfolded and functional states arising from alternate base pairing are a well-apprecia...

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Detalles Bibliográficos
Autores principales: Ditzler, Mark A., Rueda, David, Mo, Jingjie, Håkansson, Kristina, Walter, Nils G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602785/
https://www.ncbi.nlm.nih.gov/pubmed/18988629
http://dx.doi.org/10.1093/nar/gkn871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602785/
https://www.ncbi.nlm.nih.gov/pubmed/18988629
http://dx.doi.org/10.1093/nar/gkn871

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