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A rugged free energy landscape separates multiple functional RNA folds throughout denaturation
The dynamic mechanisms by which RNAs acquire biologically functional structures are of increasing importance to the rapidly expanding fields of RNA therapeutics and biotechnology. Large energy barriers separating misfolded and functional states arising from alternate base pairing are a well-apprecia...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602785/ https://www.ncbi.nlm.nih.gov/pubmed/18988629 http://dx.doi.org/10.1093/nar/gkn871 |