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Synapsis and catalysis by activated Tn3 resolvase mutants

The serine recombinase Tn3 resolvase catalyses recombination between two 114 bp res sites, each of which contains binding sites for three resolvase dimers. We have analysed the in vitro properties of resolvase variants with ‘activating’ mutations, which can catalyse recombination at binding site I o...

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Detalles Bibliográficos
Autores principales: Olorunniji, Femi J., He, Jiuya, Wenwieser, Sandra V.C.T., Boocock, Martin R., Stark, W. Marshall
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602789/
https://www.ncbi.nlm.nih.gov/pubmed/19015124
http://dx.doi.org/10.1093/nar/gkn885