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Highly individual methylation patterns of alternative glucocorticoid receptor promoters suggest individualized epigenetic regulatory mechanisms

The transcription start sites (TSS) and promoters of many genes are located in upstream CpG islands. Methylation within such islands is known for both imprinted and oncogenes, although poorly studied for other genes, especially those with complex CpG islands containing multiple first exons and promo...

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Detalles Bibliográficos
Autores principales: Turner, Jonathan D., Pelascini, Laetitia P. L., Macedo, Joana A., Muller, Claude P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602793/
https://www.ncbi.nlm.nih.gov/pubmed/19004867
http://dx.doi.org/10.1093/nar/gkn897