Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02

BACKGROUND: Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1) is a candidate vaccine antigen expressed by merozoites and sporozoites. It plays a key role in red blood cell and hepatocyte invasion that can be blocked by antibodies. METHODOLOGY/PRINCIPAL FINDINGS: We assessed the safety and imm...

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Detalles Bibliográficos
Autores principales: Roestenberg, Meta, Remarque, Ed, de Jonge, Erik, Hermsen, Rob, Blythman, Hildur, Leroy, Odile, Imoukhuede, Egeruan, Jepsen, Soren, Ofori-Anyinam, Opokua, Faber, Bart, Kocken, Clemens H. M., Arnold, Miranda, Walraven, Vanessa, Teelen, Karina, Roeffen, Will, de Mast, Quirijn, Ballou, W. Ripley, Cohen, Joe, Dubois, Marie Claude, Ascarateil, Stéphane, van der Ven, Andre, Thomas, Alan, Sauerwein, Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602972/
https://www.ncbi.nlm.nih.gov/pubmed/19093004
http://dx.doi.org/10.1371/journal.pone.0003960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602972/
https://www.ncbi.nlm.nih.gov/pubmed/19093004
http://dx.doi.org/10.1371/journal.pone.0003960

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