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Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression

Understanding stem cell-differentiation at the molecular level is important for clinical applications of stem cells and for finding new therapeutic approaches in the context of cancer stem cells. To investigate genome-wide changes involved in differentiation, we have used immortalized neural stem ce...

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Detalles Bibliográficos
Autores principales: Ahn, Sung-Min, Byun, Kyunghee, Kim, Deokhoon, Lee, Kiyoung, Yoo, Jong Shin, Kim, Seung U., Jho, Eek-hoon, Simpson, Richard J., Lee, Bonghee
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602983/
https://www.ncbi.nlm.nih.gov/pubmed/19093005
http://dx.doi.org/10.1371/journal.pone.0003917