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High Risk of Severe Anaemia after Chlorproguanil-Dapsone+Artesunate Antimalarial Treatment in Patients with G6PD (A-) Deficiency

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited human enzyme defect. This deficiency provides some protection from clinical malaria, but it can also cause haemolysis after administration of drugs with oxidant properties. METHODS: The safety of chlorprogua...

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Detalles Bibliográficos
Autores principales: Fanello, Caterina I., Karema, Corine, Avellino, Pamela, Bancone, Germana, Uwimana, Aline, Lee, Sue J., d'Alessandro, Umberto, Modiano, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603295/
https://www.ncbi.nlm.nih.gov/pubmed/19112496
http://dx.doi.org/10.1371/journal.pone.0004031