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Comparing Platforms for C. elegans Mutant Identification Using High-Throughput Whole-Genome Sequencing

BACKGROUND: Whole-genome sequencing represents a promising approach to pinpoint chemically induced mutations in genetic model organisms, thereby short-cutting time-consuming genetic mapping efforts. PRINCIPAL FINDINGS: We compare here the ability of two leading high-throughput platforms for paired-e...

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Detalles Bibliográficos
Autores principales: Shen, Yufeng, Sarin, Sumeet, Liu, Ye, Hobert, Oliver, Pe'er, Itsik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603312/
https://www.ncbi.nlm.nih.gov/pubmed/19107202
http://dx.doi.org/10.1371/journal.pone.0004012