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Comparing Platforms for C. elegans Mutant Identification Using High-Throughput Whole-Genome Sequencing
BACKGROUND: Whole-genome sequencing represents a promising approach to pinpoint chemically induced mutations in genetic model organisms, thereby short-cutting time-consuming genetic mapping efforts. PRINCIPAL FINDINGS: We compare here the ability of two leading high-throughput platforms for paired-e...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603312/ https://www.ncbi.nlm.nih.gov/pubmed/19107202 http://dx.doi.org/10.1371/journal.pone.0004012 |