Enforced Expression of the Transcriptional Coactivator OBF1 Impairs B Cell Differentiation at the Earliest Stage of Development

OBF1, also known as Bob.1 or OCA-B, is a B lymphocyte-specific transcription factor which coactivates Oct1 and Oct2 on B cell specific promoters. So far, the function of OBF1 has been mainly identified in late stage B cell populations. The central defect of OBF1 deficient mice is a severely reduced...

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Detalles Bibliográficos
Autores principales: Bordon, Alain, Bosco, Nabil, Du Roure, Camille, Bartholdy, Boris, Kohler, Hubertus, Matthias, Gabriele, Rolink, Antonius G., Matthias, Patrick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603323/
https://www.ncbi.nlm.nih.gov/pubmed/19104664
http://dx.doi.org/10.1371/journal.pone.0004007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603323/
https://www.ncbi.nlm.nih.gov/pubmed/19104664
http://dx.doi.org/10.1371/journal.pone.0004007

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