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Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Akt is a serine threonine kinase with a major role in transducing survival signals and regulating proteins involved in apoptosis. To find new interactors of Akt involved in cell survival, we performed a two-hybrid screening in yeast using human full-length Akt c-DNA as bait and a murine c-DNA librar...

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Detalles Bibliográficos
Autores principales: Garofalo, Michela, Quintavalle, Cristina, Zanca, Ciro, De Rienzo, Assunta, Romano, Giulia, Acunzo, Mario, Puca, Loredana, Incoronato, Mariarosaria, Croce, Carlo M., Condorelli, Gerolama
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603590/
https://www.ncbi.nlm.nih.gov/pubmed/19114998
http://dx.doi.org/10.1371/journal.pone.0004070