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The p38α mitogen-activated protein kinase as a central nervous system drug discovery target

Protein kinases are critical modulators of a variety of cellular signal transduction pathways, and abnormal phosphorylation events can be a cause or contributor to disease progression in a variety of disorders. This has led to the emergence of protein kinases as an important new class of drug target...

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Detalles Bibliográficos
Autores principales: Borders, Aaron S, de Almeida, Lucia, Van Eldik, Linda J, Watterson, D Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604896/
https://www.ncbi.nlm.nih.gov/pubmed/19090985
http://dx.doi.org/10.1186/1471-2202-9-S2-S12