Physiological and pathological aspects of Aβ in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators

Many studies have highlighted the pathological involvement of iron accumulation and iron-related oxidative stress (OS) in Alzheimer's disease (AD). Iron was further demonstrated to modulate expression of the Alzheimer's amyloid precursor holo-protein (APP) by a mechanism similar to that of...

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Detalles Bibliográficos
Autores principales: Avramovich-Tirosh, Yael, Amit, Tamar, Bar-Am, Orit, Weinreb, Orly, Youdim, Moussa BH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604902/
https://www.ncbi.nlm.nih.gov/pubmed/19090990
http://dx.doi.org/10.1186/1471-2202-9-S2-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604902/
https://www.ncbi.nlm.nih.gov/pubmed/19090990
http://dx.doi.org/10.1186/1471-2202-9-S2-S2

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