Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction

AIMS: We investigated the mechanism by which proinflammatory stimulation induces microvascular endothelial barrier dysfunction. Since protein phosphatase type 2A (PP2A) can mediate paracellular leak and can be inactivated by tyrosine phosphorylation in its catalytic subunit (PP2Ac), we hypothesized...

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Detalles Bibliográficos
Autores principales: Wu, Feng, Wilson, John X.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605194/
https://www.ncbi.nlm.nih.gov/pubmed/18791203
http://dx.doi.org/10.1093/cvr/cvn246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605194/
https://www.ncbi.nlm.nih.gov/pubmed/18791203
http://dx.doi.org/10.1093/cvr/cvn246

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