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Positive regulation of plasmacytoid dendritic cell function via Ly49Q recognition of class I MHC

Plasmacytoid dendritic cells (pDCs) are an important source of type I interferon (IFN) during initial immune responses to viral infections. In mice, pDCs are uniquely characterized by high-level expression of Ly49Q, a C-type lectin-like receptor specific for class I major histocompatibility complex...

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Detalles Bibliográficos
Autores principales: Tai, Lee-Hwa, Goulet, Marie-Line, Belanger, Simon, Toyama-Sorimachi, Noriko, Fodil-Cornu, Nassima, Vidal, Silvia M., Troke, Angela D., McVicar, Daniel W., Makrigiannis, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605222/
https://www.ncbi.nlm.nih.gov/pubmed/19075287
http://dx.doi.org/10.1084/jem.20080718