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Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination

DNA double-strand breaks (DSBs) introduced in the switch (S) regions are intermediates during immunoglobulin class switch recombination (CSR). These breaks are subsequently recognized, processed, and joined, leading to recombination of the two S regions. Nonhomologous end-joining (NHEJ) is believed...

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Detalles Bibliográficos
Autores principales: Du, Likun, van der Burg, Mirjam, Popov, Sergey W., Kotnis, Ashwin, van Dongen, Jacques J.M., Gennery, Andrew R., Pan-Hammarström, Qiang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605234/
https://www.ncbi.nlm.nih.gov/pubmed/19075292
http://dx.doi.org/10.1084/jem.20081915