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Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination
DNA double-strand breaks (DSBs) introduced in the switch (S) regions are intermediates during immunoglobulin class switch recombination (CSR). These breaks are subsequently recognized, processed, and joined, leading to recombination of the two S regions. Nonhomologous end-joining (NHEJ) is believed...
Autores principales: | Du, Likun, van der Burg, Mirjam, Popov, Sergey W., Kotnis, Ashwin, van Dongen, Jacques J.M., Gennery, Andrew R., Pan-Hammarström, Qiang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605234/ https://www.ncbi.nlm.nih.gov/pubmed/19075292 http://dx.doi.org/10.1084/jem.20081915 |
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