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DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors

Natural killer (NK) cells and CD8 T cells require adhesion molecules for migration, activation, expansion, differentiation, and effector functions. DNAX accessory molecule 1 (DNAM-1), an adhesion molecule belonging to the immunoglobulin superfamily, promotes many of these functions in vitro. However...

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Detalles Bibliográficos
Autores principales: Gilfillan, Susan, Chan, Christopher J., Cella, Marina, Haynes, Nicole M., Rapaport, Aaron S., Boles, Kent S., Andrews, Daniel M., Smyth, Mark J., Colonna, Marco
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605240/
https://www.ncbi.nlm.nih.gov/pubmed/19029380
http://dx.doi.org/10.1084/jem.20081752