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The Activity of HDAC8 Depends on Local and Distal Sequences of Its Peptide Substrates
[Image: see text] This paper introduces a flexible assay for characterizing the activities of the histone deacetylase enzymes. The approach combines mass spectrometry with self-assembled monolayers that present acetylated peptides and enables a label-free and one-step assay of this biochemical activ...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605276/ https://www.ncbi.nlm.nih.gov/pubmed/18470998 http://dx.doi.org/10.1021/bi800053v |