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Optimizing endothelin receptor antagonist use in the management of pulmonary arterial hypertension

Endothelin receptor antagonism has emerged as an important therapeutic approach in pulmonary arterial hypertension (PAH). Bench to bedside scientific research has shown that endothelin-1 (ET-1) is overexpressed in several forms of pulmonary vascular disease and may play an important pathogenetic rol...

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Detalles Bibliográficos
Autores principales: Steiner, M Kathryn, Preston, Ioana R
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605321/
https://www.ncbi.nlm.nih.gov/pubmed/19183742