Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity

BACKGROUND: Acetaldehyde, the first metabolite of ethanol, can generate covalent modifications of proteins and cellular constituents. However, functional consequences of such modification remain poorly defined. In the present study, we examined acetaldehyde reaction with human carbonic anhydrase (CA...

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Detalles Bibliográficos
Autores principales: Bootorabi, Fatemeh, Jänis, Janne, Valjakka, Jarkko, Isoniemi, Sari, Vainiotalo, Pirjo, Vullo, Daniela, Supuran, Claudiu T, Waheed, Abdul, Sly, William S, Niemelä, Onni, Parkkila, Seppo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605449/
https://www.ncbi.nlm.nih.gov/pubmed/19036170
http://dx.doi.org/10.1186/1471-2091-9-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605449/
https://www.ncbi.nlm.nih.gov/pubmed/19036170
http://dx.doi.org/10.1186/1471-2091-9-32

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