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Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy

BACKGROUND: Principal component analysis (PCA) and partial least square (PLS) regression may be useful to summarize the HIV genotypic information. Without pre-selection each mutation presented in at least one patient is considered with a different weight. We compared these two strategies with the co...

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Detalles Bibliográficos
Autores principales: Wittkop, Linda, Commenges, Daniel, Pellegrin, Isabelle, Breilh, Dominique, Neau, Didier, Lacoste, Denis, Pellegrin, Jean-Luc, Chêne, Geneviève, Dabis, François, Thiébaut, Rodolphe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605450/
https://www.ncbi.nlm.nih.gov/pubmed/18945369
http://dx.doi.org/10.1186/1471-2288-8-68