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Differential Requirements of Two recA Mutants for Constitutive SOS Expression in Escherichia coli K-12

BACKGROUND: Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response. The RecA-DNA filament is an allosteric effector of LexA auto-proteolysis. LexA is the...

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Detalles Bibliográficos
Autores principales: Long, Jarukit Edward, Renzette, Nicholas, Centore, Richard C., Sandler, Steven J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605550/
https://www.ncbi.nlm.nih.gov/pubmed/19116657
http://dx.doi.org/10.1371/journal.pone.0004100