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Lrp4 Modulates Extracellular Integration of Cell Signaling Pathways in Development

The extent to which cell signaling is integrated outside the cell is not currently appreciated. We show that a member of the low-density receptor-related protein family, Lrp4 modulates and integrates Bmp and canonical Wnt signalling during tooth morphogenesis by binding the secreted Bmp antagonist p...

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Detalles Bibliográficos
Autores principales: Ohazama, Atsushi, Johnson, Eric B., Ota, Masato S., Choi, Hong J., Porntaveetus, Thantrira, Oommen, Shelly, Itoh, Nobuyuki, Eto, Kazuhiro, Gritli-Linde, Amel, Herz, Joachim, Sharpe, Paul T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605561/
https://www.ncbi.nlm.nih.gov/pubmed/19116665
http://dx.doi.org/10.1371/journal.pone.0004092