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Validating Discovered Cis-Acting Regulatory Genetic Variants: Application of an Allele Specific Expression Approach to HapMap Populations

BACKGROUND: Localising regulatory variants that control gene expression is a challenge for genome research. Several studies have recently identified non-coding polymorphisms associated with inter-individual differences in gene expression. These approaches rely on the identification of signals of ass...

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Detalles Bibliográficos
Autores principales: Campino, Susana, Forton, Julian, Raj, Srilakshmi, Mohr, Bert, Auburn, Sarah, Fry, Andrew, Mangano, Valentina D., Vandiedonck, Claire, Richardson, Anna, Rockett, Kirk, Clark, Taane G., Kwiatkowski, Dominic P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605564/
https://www.ncbi.nlm.nih.gov/pubmed/19116668
http://dx.doi.org/10.1371/journal.pone.0004105