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Function and Assembly of a Chromatin-Associated RNase P that Is Required for Efficient Transcription by RNA Polymerase I

BACKGROUND: Human RNase P has been initially described as a tRNA processing enzyme, consisting of H1 RNA and at least ten distinct protein subunits. Recent findings, however, indicate that this catalytic ribonucleoprotein is also required for transcription of small noncoding RNA genes by RNA polymer...

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Detalles Bibliográficos
Autores principales: Reiner, Robert, Krasnov-Yoeli, Natalie, Dehtiar, Yana, Jarrous, Nayef
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605565/
https://www.ncbi.nlm.nih.gov/pubmed/19115013
http://dx.doi.org/10.1371/journal.pone.0004072