DNA double strand breaks activate a multi-functional genetic program in developing lymphocytes

DNA double strand breaks are generated by genotoxic agents and by cellular endonucleases as intermediates of several important physiologic processes. The cellular response to genotoxic DNA breaks includes the activation of transcriptional programs known primarily to regulate cell cycle checkpoints a...

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Detalles Bibliográficos
Autores principales: Bredemeyer, Andrea L., Helmink, Beth A., Innes, Cynthia L., Calderon, Boris, McGinnis, Lisa M., Mahowald, Grace K., Gapud, Eric J., Walker, Laura M., Collins, Jennifer B., Weaver, Brian K., Mandik-Nayak, Laura, Schreiber, Robert D., Allen, Paul M., May, Michael J., Paules, Richard S., Bassing, Craig H., Sleckman, Barry P.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605662/
https://www.ncbi.nlm.nih.gov/pubmed/18849970
http://dx.doi.org/10.1038/nature07392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605662/
https://www.ncbi.nlm.nih.gov/pubmed/18849970
http://dx.doi.org/10.1038/nature07392

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