Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]

BACKGROUND: The treatment of Herpes-simplex-virus-encephalitis (HSVE) remains a major unsolved problem in Neurology. Current gold standard for therapy is acyclovir, a drug that inhibits viral replication. Despite antiviral treatment, mortality remains up to 15%, less than 20% of patients are able to...

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Detalles Bibliográficos
Autores principales: Martinez-Torres, Francisco, Menon, Sanjay, Pritsch, Maria, Victor, Norbert, Jenetzky, Ekkehart, Jensen, Katrin, Schielke, Eva, Schmutzhard, Erich, de Gans, Jan, Chung, Chin-Hee, Luntz, Steffen, Hacke, Werner, Meyding-Lamadé, Uta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605746/
https://www.ncbi.nlm.nih.gov/pubmed/18959773
http://dx.doi.org/10.1186/1471-2377-8-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605746/
https://www.ncbi.nlm.nih.gov/pubmed/18959773
http://dx.doi.org/10.1186/1471-2377-8-40

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